T O P

Crystal structure of Bufo Alv. toxin. 5-meo-nn-dmt after drying. 1400 mag no filter..

Crystal structure of Bufo Alv. toxin. 5-meo-nn-dmt after drying. 1400 mag no filter..

dmatje

Lmao at “crystal structure”


MoleculesandPhotons

Yeah, that one pained me. If you didnt run XRD, you ain't got a crystal structure.


Ms-appropriation

We need to save the toads and use synth 5meo.


Ebenberg

[Save the toads!](https://youtu.be/qipKKBmY_LQ)


Wish_Capital

The extraction of the venom from the p. gland of the Toad is not harmful to the animal. In fact it can be beneficial by removing old stock and replacing with new..It's people that don't care that harm these animals. In fact the population of bufo alv. Is decreasing steadily while the B.Marinus is exploding and becoming invasive in Australia and Fla.etc... However cane Toad venom, well parts of it have shown promise in targeting and killing cancer cells with no damage to healthy cells when delivered by a protein to specific parts of the body. Research is relatively new but ongoing..Who knows right? Those pesky cane toads might contribute to an age old battle to cure cancer.. Of course Big Pharma will exploit it like always.. Think I'll shut up..Don't want john wick showing up at my house..Have a nice day. MCG


C10H24NO3PS

Is this image actually the crystal structure of 5-MeO-DMT or is it Incilius alvarius poison which contains many other compounds alongside 5-MeO-DMT? It looks pretty dirty and irregular to be a crystal structure


reflUX_cAtalyst

No. It's not 5-MeO-DMT. It's bufotenin, 5-HO-DMT. These are crystals under a microscope.


C10H24NO3PS

How do you know it’s bufotenin and not 5-MeO-DMT or a cocktail of everything that’s in the toad secretion?


reflUX_cAtalyst

Because bufotenin is what you get out of bufo toads.


C10H24NO3PS

5-MeO-DMT [has been isolated from](https://doi.org/10.1016/0006-2952(67)90147-5) Incilius (Bufo) alvarius, among many other alkaloids, so with bufotenin being just one of many, how do you know this is isolated bufotenin crystals?


reflUX_cAtalyst

I guess I don't. Your link is bad.


C10H24NO3PS

The link is a doi link and works for me: https://doi.org/10.1016/0006-2952(67)90147-5 DOI: 10.1016/0006-2952(67)90147-5


reflUX_cAtalyst

That one does. First one didn't. Says right there the main component is 5-HO-DMT, so it's not unreasonable to figure that's the main component of whatever is in OP's picture. There probably IS some 5-MeO-DMT in it.


MoleculesandPhotons

The term "crystal structure" doesnt apply if what you have is a mix of chemicals. There is a big difference between "some blobs that probably contain X" and "Crystal structure of X"


Sceptz

Beautiful 5-MeO-N,N-DMT. Analyzed in a legitimate laboratory or... something more home style? ^(I'm assuming it's legitimately sourced, but in case it's not, it may not be the best idea posting purified substances on the clearnet that are Schedule I, US / Schedule 9, Australia / Class A, UK.)


newstarburst

Man also posted his poppy fields and gave the state and city lol


reflUX_cAtalyst

Poppys aren't illegal to grow.


newstarburst

Still, posting poppy and another purified schedule 1 is not a good look to the DEA


reflUX_cAtalyst

No it isn't that's a fair point.


hello3pat

Tell that to historians running Thomas Jefferson's Monticello. The DEA destroyed the gardens and even confiscated their seeds for their recreation of Jefferson's poppy garden


reflUX_cAtalyst

Were they scoring and harvesting them? They're legal to grow, illegal to harvest sap from. Unless this has changed in the past couple years, but I'm quite sure it hasn't. Poppy seeds aren't illegal whatsoever. They could have fought that and won, probably just got scared because DEA is above the law.


hello3pat

No, they were not scoring them. It was puppy's being grown by historians for the fact Jefferson used to grow them. They had even contacted multiple agencies to find out if it was OK to be growing them and after they contacted the DEA the response was to go and pull up plants and confiscate seeds. The concept of "for onrimental purposes only" is absurdly loose and one of relatives was threatened by police because other people might use their plants.


reflUX_cAtalyst

So like I said, they could have easily fought that then. They got scared by scary G-men. Poppies are in peoples yards... all over, in the city I live in in PA. They aren't illegal.


reflUX_cAtalyst

No. It's bufotenin. N,N-Dimethyl-5-hydroxytryptamine. There's no methoxy group at 5 on the ring, its a hydroxyl. It's 5-HO-DMT not 5-MeO-DMT. This mistake is suuuuper common. It's not 5-meo-dmt. [Bufotenin](https://en.wikipedia.org/wiki/Bufotenin?wprov=sfla1) EDIT: people are taking to mean it's pure bufotenin. It might be, but it's NOT pure 5-MeO-DMT from a toad. It's toad venom extract, whose **major component** is bufotenin, not 5-meo-dmt. Therefore it's safe to assume that the majority of a substance is made up of it's majority component. That's not hard.


C10H24NO3PS

What you’ve said is untrue. 5-MeO-DMT has been isolated from this toad, along with numerous other alkaloids. https://doi.org/10.1016/0006-2952(67)90147-5


reflUX_cAtalyst

It's absolutely true. Bufotenin is the majority component, from your own link. It's safe to assume that the majority component is.....the majority of the substance. There probably IS some 5-MeO-DMT in there. There isn't much.


C10H24NO3PS

You’re trying to say you know it’s bufotenin, how? Other alkaloids exist in these toads. You’re implying and have explicitly stated in other comments there is no 5-MeO-DMT in these toads which is simply untrue. Read the paper I linked you to - they isolated 5-MeO-DMT from these toads and quantified it. I doubt you can determine from a single reddit photo whether this is bufotenin, 5-MeO-DMT, something else, or an impure sample of many different things. Edit: 5-MeO-DMT is 5-15% dry weight of the road secretions, which is significantly high


Sceptz

I agree that bufotenin (5-HO-N,N-DMT) is the most commonly known substituent alkaloid of the Bufo Alvarius (Incilius Alvarius) toad, My response was directly to the OP's mention of **5-MeO**\-N,N-DMT, which is also [produced in by I. Alvarius](http://sedici.unlp.edu.ar/bitstream/handle/10915/88423/Documento_completo.pdf?sequence=1). I was under the impression OP isolated the methoxylated compound from the other tryptamines. But yes, you could be correct in that the extract shown isn't pure 5-MeO-N,N-DMT.


C10H24NO3PS

Replying to your edit: do you know what (if any) extraction and purification method OP used? What if they isolated and crystallised 5-MeO-DMT from the excretion?


AtenderhistoryinrusT

There are countless photos of his bufo frogs in his comments, dude is home growing 5-MeO. This dude does not give a fuck.


Jakealive7

“Crystal”


RustyScrewInBogWater

Lol toads


Wish_Capital

Ok ok let me splain Lucy. You are all right.. There are many other alks and toxins in this sample..1st off a Toad didn't die to provide this. 2nd It still needs to be combusted to become 5-meo-nn-dmt. No this isn't cane Toad venom . I was bored and playing with my very cool toads Fred and Ethal last night. Apparently Fred didn't enjoy being handled and tried to kill me..SO being ME. I wanted to do an oil emersion and bypass the optical level of my omax scope but could find neither my oil or my filters.In fact even my dyes had dried up. I think it's beautiful and interesting..You guys are brutal here! No need to argue and infight. I say just enjoy. I'm an old man and have worked with biotoxins for years. I believe them to be useful in a lot of different uses..Your all right about your opinions. Yes synthetic is less harmful to the Sanoran desert or Colorado River Toad. Funny thing is no toads have been seen in the Co. River basin for many many years. My point is that it is an interesting and useful molecule. If your interested just look up Dr. Octavia Rettig in Mexico or just Sapo in general. The Shamen Toad venom has been used for hundreds if not thousands of years by the native peoples all over the planet... I appreciate all the positive comments and even the negative. Lots of great and brilliant minds out there. I'm super impressed by the collective knowledge of this sub. Imagine what we could accomplish if we could all get along?? We could change the world... If anyone has any interest in biotoxins or questions about any new applications or the state of the research at this time not just in my lab but world wide DM me. I try to stay current best I can. MCG


Psychedellyfish

Did you extract it yourself?


harry_lawson

Nice try, FBI.


Psychedellyfish

You got me. This time...


Brogogo2

All I see is bacon


CPT_XxPANDAxX

I thought it was bacon 🥓


reflUX_cAtalyst

Bufotenin isn't 5-Meo-DMT. It's 5-HO-DMT. 5-meo-dmt doesn't come from toads.


C10H24NO3PS

Yes it does: https://doi.org/10.1016/0006-2952(67)90147-5 5-MeO-DMT is 5-15% dry weight of the toad secretions, which is significantly high


patrik3031

"toxin"


Pd473262

How can I get into research with psychedelic related stuff? Is it possible with my chemistry degree?


Wish_Capital

You could certainly start with that. Research on psycs falls under a huge umbrella. First of you need to find a lab thats doing that type of work and try to get in as a general chemist. Or you can go back to school and get into pharma chem. I know U of M in annarbor mi. has a program for psyc. Chem!! I have a few hookups there but DM me whereabouts you live and Ill see what I can do.. I have a large group of pros I work with like Paul Stamets the Mycologist. He came up with mushroom mycelium that could eat and digest oil poopin it out as a biodegradable non toxic byproduct they used it on the exon spill But his work with Psilocybin mushrooms is nothing short of legendary. If your truly interested you will need to do some digging around. Psyc chemists and researchers are a different breed. Its also quite regulated. My dea license for this year alone was astronomical. Bottom line is you kinda gotta know someone in the field and have a vast knowledge of Pharma chem.. Ill see what I can come up with for ya.. If thats your passion Youll get in just stay focused and dont give up.. MCG