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This seems bad. > T cell responses are more durable That's been my understanding as well, and so does this open the door for more antigenic sin? Does anyone know how long T responses take to evolve to meet the challenges of new variants? I saw one source speculate around a year, but I don't think there's really much data on this (for any diseases.) Am I mistaken?


This paper goes over my head so I’m hoping someone who understands it can explain. Fig 4 seems to only have 4 plots that include Omicron and cytokine release for 2 of the 4 is zero. But previous studies have been posted implying that 80%+ of epitopes are conserved. And for this particular study only the spike epitopes are looked at.